Ahmed Atef Ahmed

Ahmed Atef Ahmed

Postdoctoral Fellow

About Me

Ahmed Atef Ahmed Ali obtained his PhD degree in 2017 in the Molecular and Cell Biology program of Academia Sinica and National Defense Medical Center under the supervision of professor Hsu-Shan Huang where he was awarded the first position excellence award for academic achievements among the PhD graduates of Academia Sinica and National Defense Medical Center. He obtained his MSc of Pharmaceutical Sciences in Microbiology and Immunology and BSc (HONS) of pharmaceutical sciences from Cairo University. With the assistance of professor Cheng-Yu Chen in Taipei Medical University, Ahmed was able to develop a smart biomarker theranostic probe for therapeutic and diagnostic applications of cancers using the magnetic resonance imaging (MRI). Ahmed also investigated the molecular signaling pathways that account for the therapeutic activities of various novel drugs developed by his research group. Moreover, Ahmed studied the microbiological properties and activities of sterile pharmaceutical preparations. Currently, Ahmed is a licensed clinical diagnostic and medical microbiologist. Besides the research experience, Ahmed has extensive academic teaching experience, that is evident from promoting from an academic researcher to teaching assistant to assistant lecturer to senior assistant lecturer in Faculty of Pharmacy and Faculty of Dentistry, where he was awarded several awards for his exceptional academic and teaching achievements.

Work Experience

Postdoctoral fellow, Translational Imaging Research Center, Taipei Medical University, Taipei

May 2017 - Present

Senior assistant lecturer, Faculty of Pharmacy and Faculty of Dentistry, Misr International University, Cairo

2003-2011

Academic researcher, Faculty of Pharmacy, Cairo University

2005-2010

Research Interests

Theranostic biomarker probes
Stem cell & Cancer research
Drug discovery & development
Drug delivery systems
Microbiology (pharmaceutical, diagnostic & medical)

Awards

Received the Honorary “First Excellence Academic Performance award for the cumulative academic achievements among Academia Sinica and National Defence Medical Center PhD graduates, June 2017.
Awarded the “TIGP Student Conference Travel Grant” from Academia Sinica; Sep-Dec 2016.
Awarded the “International Conference Travel Grant” from Ministry of Science & Technology, Taiwan; May 2016.
Awarded the "Shield of Excellence" award from the Egyptian Pharmacist Syndicate for the scientific achievements in 2010.
Awarded the “Academic Award Achievement” award from Misr International University for my research achievements in 2010.
Awarded the “Outstanding and Commendable Performance” award from Misr International University for my academic educational achievements in 2009.

Invited conference talks

Formulation of smart anticancer drug-loaded nanoparticles for magnetic resonance imaging applications – TMU experience, invited talk at the 2017 International Biomedical Interface Symposium, hosted by Tokyo University of Science.
A facile and effective strategy to identify molecular targets of drugs and biological lead compounds, selected by the organizing committee for invited talk at the 15th International Meeting of the Consortium for Globalization of Chinese Medicine, hosted by Academia Sinica.

Publications

Journal

Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI.

Ahmed Ali AA, Hsu FT, Hsieh CL, Shiau CY, Chiang CH, Wei ZH, Chen CY, Huang HS. Scientific Reports, 2016.

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Novel Anthra[1,2-c][1,2,5]Thiadiazole-6,11-Diones as Promising Anticancer Lead Compounds: Biological Evaluation, Characterization & Molecular Targets Determination.

Ahmed Ali AA, Lee YR, Chen TC, Chen CL, Lee CC, Shiau CY, Chiang CH, Huang HS. PLOS ONE, 2016.

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Design, synthesis and SARs of novel salicylanilides as potent inhibitors of RANKL-induced osteoclastogenesis and bone resorption.

Chen CL; Lee CC; Liu FL; Chen TC; Ahmed Ali AA; Chang DM; Huang HS. Eur J Med Chem, 2016.

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Novel inhibitors of RANKL-induced osteoclastogenesis: Deign, synthesis, and biological evaluation of 6-(2,4-difluorophenyl)-3-phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-diones.

Lee CC; Liu FL; Chen CL; Chen TC; Liu FC; Ahmed Ali AA; Chang DM; Huang HS. Bioorg Med Chem, 2015.

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Synthesis and evaluation of new 3-substituted-4-chloro-thioxanthone derivatives as potent anti-breast cancer agents.

Chen CL, Chen TC, Lee CC, Shih LC, Lin CY, Hsieh YY, Ahmed Ali AA, Huang HS. Arab J Chem, 2015.

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Ring fusion strategy for synthesis and lead optimization of sulfur-substituted anthra[1,2-c][1,2,5]thiadiazole-6,11-diones as promising scaffold of antitumor agents.

Lee YR; Chen, TC; Lee CC; Chen CL; Ahmed Ali AA; Tikhomirov A; Guh JH; Yu DS; Huang HS. Eur J Med Chem, 2015.

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Modified salicylanilide and 3-phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-dione derivatives as novel inhibitors of osteoclast differentiation and bone resorption

Chen CL; Liu FL; Lee CC; Chen TC; Ahmed Ali AA; Sytwu HK; Chang DM; Huang HS. J Med Chem, 2014.

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Ring Fusion Strategy for the Synthesis of Anthra[2,3-d]oxazole-2-thione-5,10-dione Homologues as DNA Topoisomerase Inhibitors and as Antitumor Agents.

Chen CL; Liu FL; Lee CC; Chen TC; Chang WW; Guh JH; Ahmed Ali AA; Chang DM; Huang HS. Eur J Med Chem. 2014.

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Formulation of smart cancer-targeted theranostic nanoparticles, molecular targets identification and biological evaluation of small-molecule drugs

A thesis submitted to Molecular and Cell Biology Program, Taiwan International Graduate Program of National Defense Medical Center and Academia Sinica in partial fulfillment of the requirements for the Degree of philosophy in Molecular and Cell Biology.

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A study of the microbial quality, preservation and safety of some ophthalmic pharmaceutical and cosmetic preparations.

A thesis submitted to Faculty of Pharmacy, Cairo University in partial fulfillment of the requirements for the Degree of Master of Pharmaceutical Sciences in Microbiology and Immunology.

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