Chia-Feng(Alvin) Lu

Research Fellow

About Me

Chia-Feng (Alvin) Lu attained his Ph.D. at Department of Biomedical Imaging and Radiological Sciences in 2012 from the National Yang-Ming University under the mentorship of Professor Yu-Te Wu. His dissertation explored the organization of brain structural network for the patients with ponto-cerebellar atrophy from the perspective of local structure to global network efficiency using diffusion tensor images. From summer 2013 to summer 2014, He took a one-year project assistant professor position in Department of Physical Therapy and Assistive Technology at National Yang-Ming University and also worked as an adjunct assistant research fellow in Taipei City Hospital. He gave lectures of “MATLAB programming for medical signal analysis” and “Principles and applications of magnetic resonance imaging” for graduate students during past two semesters at National Yang-Ming University and released lesson videos and materials on the internet for free to facilitate students’ learning. He collaborated with Professor Ray-Yau Wang to research the control mechanism form neural activities in human locomotion with dual-task interference using functional near-infrared spectroscopy. A major focus recently is to develop an image platform in performing brain tissue classification, estimating vascular permeability, and characterizing venous drainage based on MRI, aiming to understanding the brain circulation for both arterial and venous systems in vivo under the effects of neurovascular diseases. The issue of patentability and the subsequent technique transfer for the developing techniques and platforms is of interest to him.

Research Interests

Neuroimaging
Functional near-infrared spectroscopy
Brain network analysis

Work Experience

Research Fellow, Imaging Research Center, Taipei Medical University, Taipei

September 2014 – Present

Adjunct Assistant Professor, Department of Physical Therapy and Assistive Technology, National Yang-Ming University, Taipei

September 2014 – Present

Assistant Professor, Department of Physical Therapy and Assistive Technology, National Yang-Ming University, Taipei

August 2013 – August 2014

Adjunct Assistant Research Fellow, Taipei City Hospital, Taipei

January 2014 – July 2014

Postdoctoral Fellow, Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei

January 2013 – July 2013

Invited Talk

June 2013: Clinical applications of monitoring brain circulation, Stroke and Neurovascular Center, Taipei Veterans General Hospital, Taipei, Taiwan.


November 2013: Introduction of tissue classification techniques of DSC-MRI and fNIRS applications, Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan.


Publications

Reorganization of Functional Connectivity during the Motor Task Using EEG Time-frequency Cross Mutual Information Analysis.

Chia-Feng Lu, Shin Teng, Chih-I Hung, Po-Jung Tseng, Liang-Ta Lin, Po-Lei Lee, Yu-Te Wu. Clinical Neurophysiology, 122:1569-1579, 2011 (IF: 3.144, Rank: 54/191= 28.3%)

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Disrupted Cerebellar Connectivity Reduces Whole-Brain Network Efficiency in Multiple System Atrophy.

Chia-Feng Lu, Bing-Wen Soong, Hsiu-Mei Wu, Shin Teng, Po-Shan Wang, Yu-Te Wu.Movement Disorders, 28(3):362-369, 2013 (IF: 4.558, Rank: 23/191= 12.0%).

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Medullo-ponto-cerebellar White Matter Degeneration Altered Brain Network Organization and Cortical Morphology in Multiple System Atrophy.

Chia-Feng Lu, Po-Shan Wang, Yuan-Lin Lao, Hsiu-Mei Wu, Bing-Wen Soong, Yu-Te Wu. Brain Structure & Function, 219(3):947-958, 2014 (IF: 7.837, Rank: 1/21= 4.7%; 18/251=7.1%). Key Research Article on Psychology Progress.

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Hemodynamic Segmentation of Brain Perfusion Images with Delay and Dispersion Effects Using an Expectation-Maximization Algorithm.

Chia-Feng Lu, Wan-Yuo Guo, Feng-Chi Chang, Shang-Ran Huang, Yen-Chun Chou, Yu-Te Wu. PLoS ONE, 8(7): e68986, 2013(IF= 3.739, Rank: 7/56=12.5%).

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Altered Resting-State Functional Connectivity of Striatal-Thalamic Circuit in Bipolar Disorder.

Shin Teng, Chia-Feng Lu*, Po-Shan Wang, Cheng-Ta Li, Pei-Chi Tu, Chih-I Hung, Tung-Ping Su, Yu-Te Wu. PLoS ONE, 9(5): e96422, 2014 (IF= 3.739, Rank: 7/56=12.5%). * : equal contribution

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Three-Dimensional Reconstruction of Cranial Defect Using Active Contour Model and Image Registration.

Yuan-Lin Liao, Chia-Feng Lu, Yung-Nien Sun, Chieh-Tsai Wu, Jiann-Der Lee, Shih-Tseng Lee, Yu-Te Wu. Medical & Biological Engineering & Computing, 49(2): 203-211, 2011 (IF: 1.790, Rank: 29/99= 29.3%).

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Using Three-Dimensional Multigrid-Based Snake and Multiresolution Image Registration for Reconstruction of Cranial Defect.

Yuan-Lin Liao, Chia-Feng Lu, Chieh-Tsai Wu, Jiann-Der Lee, Shih-Tseng Lee, Yung-Nien Sun, Yu-Te Wu. Medical & Biological Engineering & Computing, 51,89-101, 2013 (IF: 1.790, Rank: 29/99= 29.3%).

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Blind Source Separation of Hemodynamics from Magnetic Resonance Perfusion Brain Images Using Independent Factor Analysis.

Yen-Chun Chou, Chia-Feng Lu, Wan-Yuo Guo and Yu-Te Wu. Mathematical Methods for Images and Surfaces in International Journal of Biomedical Imaging, 2010, 360568. (EI)

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Cortical Shape and Curvedness Analysis of Structural Deficits in Remitting and Non-remitting Depression.

Yuan-Lin Liao, Po-Shan Wang, Chia-Feng Lu, Chih-I Hung, Cheng-Ta Li, Ching-Po Lin, Jen-Chuen Hsieh, Tung-Ping Su, Yu-Te Wu. PLoS ONE, 8(7):e68625, 2013 (IF= 3.739, Rank: 7/56=12.5%).

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Co-activation of primary motor cortex ipsilateral to muscles contracting in a unilateral motor task.

Shin-Yi Chiou, Ray-Yau Wang, Kwong-Kum Liao, Yu-Te Wu, Chia-Feng Lu, Yea-Ru Yang. Clinical Neurophysiology, 124:1353-1363, 2013 (IF: 3.144, Rank: 54/191= 28.3%).

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Sculpting the intrinsic modular organization of spontaneous brain activity by art.

Chia-Shu Lin, Yong Liu, Wei-Yuan Huang,Chia-Feng Lu, Shin Teng, Tzong-Ching Ju, Tianzi Jiang, Yong He, Yu-Te Wu, Jen-Chuen Hsieh. PLoS ONE, 8(6):e66761, 2013 (IF= 3.739, Rank: 7/56=12.5%).

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Fractional Anisotropy in Corpus Callosum is Associated with Facilitation of Motor Representation during Ipsilateral Hand Movements.

Shin-Yi Chiou, Ray-Yau Wang, R. Edward Roberts, Yu-Te Wu, Chia-Feng Lu, Kwong-Kum Liao, Yea-Ru Yang. PLoS ONE, 9(8):e104218, 2014 (IF= 3.739, Rank: 7/56=12.5%).

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Effects of Score Transformation on the Composite Scores under the Multivariate Proficiency Distribution Using IRT.

Shun-Wen Chang, Shin Teng, Chia-Feng Lu. Psychological Testing, 60(3):457-488, 2013 (TSSCI).

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Explorations of Composite Scores under the Multivariate Proficiency Distribution Using IRT.

Shun-Wen Chang, Shin Teng, Chia-Feng Lu. Bulletin of Educational Psychology, 45(2):261-278, 2013 (TSSCI).

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Explorations of Composite Scores under the Multivariate Proficiency Distribution Using IRT.

Shun-Wen Chang, Shin Teng, Chia-Feng Lu. Bulletin of Educational Psychology, 45(2):261-278, 2013 (TSSCI).

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Maintaining Gait Performance by Cortical Activation with Dual-Task Interference: A Functional Near-Infrared Spectroscopy Study.

Chia-Feng Lu, Yan-Ci Liu, Yea-Ru Yang, Yu-Te Wu, Ray-Yau Wang. Submitted to PLoS ONE.

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